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Ziprasidone hydrochloride

CAS No. 122883-93-6

Ziprasidone hydrochloride ( CP88059 hydrochloride;CP 88059 hydrochloride )

产品货号. M10892 CAS No. 122883-93-6

A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥405 有现货
25MG ¥689 有现货
50MG ¥1094 有现货
100MG ¥1369 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ziprasidone hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.
  • 产品描述
    A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors; exhibits potent antipsychotic activity in vivo.Schizophrenia Approved
  • 同义词
    CP88059 hydrochloride;CP 88059 hydrochloride
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HTtransporter;5-HT1A;5-HT1B;5-HT1D;5-HT2A;5-HT2C;5-HT6;5-HT7;D1;D2;D3;H1receptor;norepinephrinetransporter(NET);α1A-adrenergicreceptor;α2A-adrenergicreceptor
  • 研究领域
    Neurological Disease
  • 适应症
    Schizophrenia

化学信息

  • CAS Number
    122883-93-6
  • 分子量
    449.40
  • 分子式
    C21H22Cl2N4OS
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    Cl.ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
  • 化学全称
    2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride (1:1)

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
产品手册
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